Product Description: VCP Activator 1 is a VCP activator that dose-dependently stimulates VCP ATPase activity. VCP Activator 1 binds an allosteric pocket near the C-terminus. In addition, VCP Activator 1 binding site can also be occupied by a phenylalanine residue in the VCP C-terminal tail[1].
Applications: Cancer-programmed cell death
Formula: C20H22N2O2S
References: [1]Jones NH, et al. Allosteric activation of VCP, a AAA unfoldase, by small molecule mimicry. bioRxiv [Preprint]. 2023 Oct 2:2023.10.02.560478.
Molecular Weight: 354.47
Compound Purity: 99.71
Research Area: Others
Solubility: DMSO : 300 mg/mL (ultrasonic)
Target: p97