VEGFR2 Kinase Inhibitor I, CAS 15966-93-5

Shelf life (days): 1460.0

Formulation: A crystalline solid

Formal Name: 5-[(1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxylic acid, ethyl ester

Purity: ≥95%

Formula Markup: C18H18N2O3

Formula Weight: 310.4

CAS Number: 15966-93-5

Notes: Vascular endothelial growth factor receptor 2 (VEGFR2, also known as KDR and FLK1) is a receptor tyrosine kinase that regulates angiogenesis, vascular development, and embryonic hematopoiesis in response to VEGF isoforms A, C, and D. VEGFR2 kinase inhibitor I is a potent, cell-permeable inhibitor of mouse VEGFR2 kinase (IC50 = 70 nM).{28800} It has little or no effect against receptors for platelet-derived growth factor, epidermal growth factor, or insulin-like growth factor (IC50 > 100 µM).{28800}

• Artikelnummer: CAY13578-10
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 13578-10
• Verpackungseinheit: 10 mg
• Mengeneinheit: STK