(±)-Vesamicol (hydrochloride), CAS 120447-62-3

Shelf life (days): 1460.0

Formulation: A solid

Formal Name: (1R,2R)-rel-2-(4-phenyl-1-piperidinyl)-cyclohexanol, monohydrochloride

Purity: ≥98%

Formula Markup: C17H25NO / HCl

Formula Weight: 295.851

CAS Number: 120447-62-3

Notes: An ACh uptake inhibitor (IC50 = 40 nM) and neuromuscular blocking agent; binds to the vesamicol receptor (Ki = 2 nM), as well as σ1- and σ2-receptors (Kis = 26 and 34 nM, respectively); inhibits electrically induced maximal twitches of tibialis anterior muscles in anesthetized cats at 150 µg/kg; induces transient flaccid paralysis in conscious mice when administered intravenously or orally (ED50s = 2.7 and 35.5 mg/kg, respectively); decreases REM sleep frequency and duration in rats at 80 or 100 µg/animal

• Artikelnummer: CAY43150-50
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 43150-50
• Verpackungseinheit: 50 mg
• Mengeneinheit: STK