Product Description: Vesatolimod (GS-9620) is a potent, selective and orally active agonist of Toll-Like Receptor (TLR7) with an EC50 of 291 nM.
Applications: COVID-19-anti-virus
Formula: C22H30N6O2
References: [1]Rebbapragada I, et al. Molecular Determinants of GS-9620-Dependent TLR7 Activation. PLoS One. 2016 Jan 19;11(1):e0146835./[2]Lanford RE, et al. GS-9620, an Oral Agonist of Toll-Like Receptor-7, Induces Prolonged Suppression of Hepatitis B Virus in Chronically Infected Chimpanzees. Gastroenterology. 2013 Feb 13. pii: S0016-5085(13)00169-8./[3]D Tumas, et al. Preclinical Characterization of GS-9620, A Potent and Selective Oral TLR7 Agonist.
CAS Number: 1228585-88-3
Molecular Weight: 410.51
Compound Purity: 99.90
Research Area: Inflammation/Immunology
Solubility: DMSO : ≥ 16.67 mg/mL
Target: Apoptosis;HBV;HCV;HIV;Toll-like Receptor (TLR)
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