Vesnarinone, CAS 81840-15-5

Description: Vesnarinone (Arkin) (INN) is a mixed phosphodiesterase 3 inhibitor and ion-channel modifier that has modest, dose-dependent, positive inotropic activity, but minimal negative chronotropic activity. It also suppresses cell proliferation and induces apoptosis by inducing the expression of p21, an inhibitor of cyclin-dependent kinase activity in p53-mediated cell cycle arrest.

CAS Number: 81840-15-5

Formula: C22H25N3O4

Molecular Weight: 395,45

References: Katayama Y, et al. Inhibitory effects of Vesnarinone on cloned cardiac delayed rectifier K(+) channels expressed in a mammalian cell line. J Pharmacol Exp Ther. 2000 Jul;294(1):339-46.

• Artikelnummer: TGMT3465-100mg
• Hersteller: TargetMol Chemicals
• Hersteller Artikelnummer: T3465-100mg
• Verpackungseinheit: 100 mg
• Mengeneinheit: STK