Target: VGLUT3
Conjugate: RPE
Product Type: Monoclonal
Clone Number: N34/34 (Formerly sold as S34-34)
Immunogen: Fusion protein amino acids 546-588 (cytoplasmic C-terminus) of rat VGLUT3
Swiss-Prot: Q7TSF2
Purification: Protein G Purified
Storage Buffer: 95.64mM Phosphate, 2.48mM MES and 2mM EDTA
Concentration: 1 mg/ml
Specificity: Detects ~65kDa.
Cellular Localization: Cytoplasmic Vesicle / Secretory Vesicle / Synaptic Vesicle Membrane / Membrane / Cell Junction / Synapse
Scientific Background: Vesicular Glutamate Transporter 3 (VGLUT3) is a multipass membrane protein restricted to synaptic vesicles of glutamergic neurons. It is specifically expressed in amygdala, cerebellum, hippocampus, medulla, spinal cord, and thalamus. Human VGLUT3 shares a 72% sequence homology with VLGUT2 and BNPI.
References: 1. Amilhon B., et al. (2010) J Neurosci. 30(6): 2198-2210.2. Herzog E., et al. (2004) Neurosci. 123(4): 983-1002.
Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
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