Voruciclib, CAS 1000023-04-0

Description: Voruciclib is an orally active and selective CDK inhibitor (Ki: 0.626 nM-9.1 nM). Voruciclib represses the expression of MCL-1 in multiple models of diffuse large B-cell lymphoma. Voruciclib effectively blocks CDK9, the transcriptional regulator of MCL-1.

CAS Number: 1000023-04-0

Formula: C22H19ClF3NO5

Molecular Weight: 469,84

References: Dey J, et al. Voruciclib, a clinical stage oral CDK9 inhibitor, represses MCL-1 and sensitizes high-risk Diffuse Large B-cell Lymphoma to BCL2 inhibition. Sci Rep. 2017 Dec 21;7(1):18007.

• Artikelnummer: TGMT10096L-1mL
• Hersteller: TargetMol Chemicals
• Hersteller Artikelnummer: T10096L-1mL
• Verpackungseinheit: 1 mL
• Mengeneinheit: STK