Product Description: WNK1-IN-1 is a selective inhibitor of WNK1 with an IC50 value of 1.6 μM. WNK1-IN-1 inhibits OSR1 phosphorylation with an IC50 value of 4.3 μM. WNK1-IN-1 can be used for the research of blood pressure regulation and cancer[1].
Applications: Cancer-Kinase/protease
Formula: C13H15BrCl2N2O4S
References: [1]Rodriguez M, et al. Synthesis and Structural Characterization of Novel Trihalo-sulfone Inhibitors of WNK1. ACS Med Chem Lett. 2022 Sep 23;13(10):1678-1684.