Product Description: WZ4002 is a mutant selective EGFR inhibitor with IC50s of 2, 8, 3 and 2 nM for EGFRL858R, EGFRL858R/T790M, EGFRE746_A750 and EGFRE746_A750/T790M, respectively.
Applications: Cancer-Kinase/protease
Formula: C25H27ClN6O3
References: [1]Zhou W, et al. Novel mutant-selective EGFR kinase inhibitors against EGFR T790M.Nature. 2009 Dec 24;462(7276):1070-4.
CAS Number: 1213269-23-8
Molecular Weight: 494.97
Compound Purity: 99.76
Research Area: Cancer
Solubility: DMSO : 10 mg/mL (ultrasonic)
Target: EGFR