X-376, CAS 1365267-27-1

Product Description: X-376 is a potent and highly specific ALK tyrosine kinase inhibitor (TKI) (IC50=0.61 nM). X-376 is a less potent inhibitor of MET (IC50=0.69 nM). X-376 displays potent anti-tumor activity[1].

Applications: Cancer-Kinase/protease

Formula: C25H25Cl2FN6O3

References: [1]Lovly CM, et al. Insights into ALK-driven cancers revealed through development of novel ALK tyrosine kinaseinhibitors. Cancer Res. 2011 Jul 15;71(14):4920-31.

CAS Number: 1365267-27-1

Molecular Weight: 547.41

Compound Purity: 98.10

Research Area: Cancer

Solubility: DMSO : ≥ 37 mg/mL

Target: Anaplastic lymphoma kinase (ALK);c-Met/HGFR

• Artikelnummer: MEXHY-16590-100
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-16590-100
• Verpackungseinheit: 100 mg
• Mengeneinheit: STK