XMD17-109, CAS 1435488-37-1

Product Description: XMD17-109 is a novel, specific ERK-5 inhibitor, with an IC50 of 162 nM.

Applications: Cancer-Kinase/protease

Formula: C36H46N8O3

References: [1]Deng X, et al. Structural determinants for ERK5 (MAPK7) and leucine rich repeat kinase 2 activities of benzo[e]pyrimido-[5,4-b]diazepine-6(11H)-ones. Eur J Med Chem. 2013;70:758-67./[2]Elkins, Jonathan M., et al. X-ray Crystal Structure of ERK5 (MAPK7) in Complex with a Specific Inhibitor. Journal of Medicinal Chemistry (2013), 56(11), 4413-4421./[3]Wilhelmsen K, et al. Extracellular signal-regulated kinase 5 promotes acute cellular and systemic inflammation. Sci Signal. 2015 Aug 25;8(391):ra86.

CAS Number: 1435488-37-1

Molecular Weight: 638.80

Compound Purity: 99.20

Research Area: Cancer

Solubility: DMSO : 100 mg/mL (ultrasonic;warming;heat to 60°C)

Target: ERK

• Artikelnummer: MEXHY-15665-10.1
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-15665-10.1
• Verpackungseinheit: 10 mM/1 ml
• Mengeneinheit: STK