XY-06-007, CAS 2757045-94-4

Product Description: XY-06-007 is a selective and potent bump-and-hole (B&H)-PROTAC BRD4BD1L94V degrader. XY-06-007 shows a DC50, 6 h of 10 nM against BRD4BD1L94V with no degradation of off-targets. XY-06-007 demonstrates suitable pharmacokinetics for in vivo studies[1].

Applications: Cancer-programmed cell death

Formula: C41H41ClN8O8

References: [1]Radosław P Nowak, et al. Structure-Guided Design of a "Bump-and-Hole" Bromodomain-Based Degradation Tag. J Med Chem. 2021 Aug 12;64(15):11637-11650.

CAS Number: 2757045-94-4

Molecular Weight: 809.27

Compound Purity: 98.9

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: Epigenetic Reader Domain;PROTACs

• Artikelnummer: MEXHY-145226-1
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-145226-1
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK