Pruvonertinib, CAS 2064269-82-3

Product Description: YK-029A is an orally active inhibitor of mutant EGFR，targeting to both the T790M mutations (EGFRT790M) and exon 20 insertion of EGFR (EGFRex20ins). YK-029A exhibits significant antitumor activity，and results tumor regression in EGFRex20ins-driven PDX models[1].

Applications: Cancer-Kinase/protease

Formula: C27H32N8O2

References: [1]Liu B, et al. Discovery of YK-029A, a novel mutant EGFR inhibitor targeting both T790 M and exon 20 insertion mutations, as a treatment for NSCLC. Eur J Med Chem. 2023 Oct 5;258:115590.

CAS Number: 2064269-82-3

Molecular Weight: 500.60

Compound Purity: 99.50

Research Area: Cancer

Solubility: DMSO : 100 mg/mL (ultrasonic)

Target: EGFR

• Artikelnummer: MEXHY-155537-10
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-155537-10
• Verpackungseinheit: 10 mg
• Mengeneinheit: STK