YYA-021, CAS 144217-65-2

Shelf life (days): 1460.0

Formulation: A crystalline solid

Formal Name: N1-(4-methylphenyl)-N2-(2,2,6,6-tetramethyl-4-piperidinyl)-ethanediamide

Purity: ≥98%

Formula Markup: C18H27N3O2

Formula Weight: 317.4

CAS Number: 144217-65-2

Notes: YYA-021 is a small molecule CD4 mimetic that competitively inhibits gp120 from interacting with CD4, preventing HIV entry into cells.{40117} It inhibits infection of PM1/CCR5 cells from lab isolates of the HIV-1 strains IIIB (X4, Sub B) and 89.6 (dual, Sub B) (IC50s = 23 and 41 µM, respectively) as well as clinical isolates of the fTOI (R5, Sub B) and KYAG strains (R5, Sub B) (IC50s = 16 and 51 µM, respectively). It also inhibits HIV-1 infection of TZM-bl cells (IC50 = 8.4 µM) and reduces viability of mock-infected PM1/CCR5 cells with cytotoxic concentration (CC50) values of 260 µM.{40116}

• Artikelnummer: CAY22915-10
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 22915-10
• Verpackungseinheit: 10 mg
• Mengeneinheit: STK