Product Description: Z433927330 is a potent and selective inhibitor of Aquaporin-7 (AQP7), less potently inhibits AQP3 and AQPs9, with IC50s of ~0.2 µM, ~0.7 µM and ~1.1 µM for mAQP7, mAQP3 and mAQP9, respectively[1].
Formula: C20H20N4O3
References: [1]Z433927330, et al. Identification and characterization of potent and selective aquaporin-3 and aquaporin-7 inhibitors. J Biol Chem. 2019 May 3;294(18):7377-7387.
CAS Number: 1005883-72-6
Molecular Weight: 364.40
Compound Purity: 98.11
Research Area: Others
Solubility: DMSO : ≥ 280 mg/mL
Target: Aquaporin