Shelf life (days): 1460.0
Formulation: A crystalline solid
Formal Name: 3’-azido-3’-deoxy-thymidine
Purity: ≥98%
Formula Markup: C10H13N5O4
Formula Weight: 267.3
CAS Number: 30516-87-1
Notes: Zidovudine is a nucleoside reverse transcriptase inhibitor (NRTI).{64428} It is phosphorylated intracellularly to its active form zidovudine-5’-triphosphate by the successive actions of thymidine kinase, thymidylate kinase, and nucleoside diphosphate kinase.{61905} Zidovudine (0.01, 0.1, and 1 µM) reduces HIV-1 p24 antigen levels in the culture supernatant of HIV-1-infected isolated human peripheral blood monocytes.{64429} Formulations containing zidovudine have been used in the treatment of HIV infections.