Shelf life (days): 1460.0
Formulation: A crystalline solid
Formal Name: 4-[2-[[7-amino-2-(2-furanyl)[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-yl]amino]ethyl]-phenol
Purity: ≥98%
Formula Markup: C16H15N7O2
Formula Weight: 337.3
CAS Number: 139180-30-6
Notes: ZM 241385 is a potent antagonist of A2A adenosine receptors (pIC50 = 9.52 for displacement of 5’-N-ethylcarboxamidoadenosine from rat phaeochromocytoma cell membranes).{32870,27926} It displays little or no activity at other A adenosine receptors. ZM 241385 is active in vivo.{32869,32871} It acts as an inverse agonist at constitutively active mutants of the human A2B adenosine receptor.{32641}