Product Description: Zoliflodacin (ETX0914;AZD0914) is a novel spiropyrimidinetrione bacterial DNA gyrase/topoisomerase inhibitor. Zoliflodacin has potent in vitro antibacterial activity against Gram-positive and Gram-negative organisms, including S. aureus with the MIC90 of 0.25 μg/mL.
Applications: COVID-19-anti-virus
Formula: C22H22FN5O7
References: [1]Huband MD, et al. In vitro antibacterial activity of AZD0914, a new spiropyrimidinetrione DNA gyrase/topoisomerase inhibitor with potent activity against Gram-positive, fastidious Gram-Negative, and atypical bacteria. Antimicrob Agents Chemother. 2015 Jan;59(1):467-74.
CAS Number: 1620458-09-4
Molecular Weight: 487.44
Compound Purity: 99.95
Research Area: Infection
Solubility: DMSO : 140 mg/mL (ultrasonic)
Target: Antibiotic;Bacterial;DNA/RNA Synthesis