Target: LAG3
Clone: C9B7W
Specificity: Anti-LAG-3 In Vivo Antibody - Ultra Low Endotoxin (C9B7W) recognizes an epitope on Mouse LAG-3
Purification method: This monoclonal antibody was purified using Protein G
Antigen Distribution: T-cells and NK cells
Background: LAG-3, also known as CD223, is 70 kD type I transmembrane glycoprotein within the Ig superfamily. CD223, like CD4, binds MHC class II molecules, but with higher affinity than CD4. Clone C9B7W antibody has been reported to block the function of murine LAG-3 in vivo and in vitro.
Immunogen: Murine CD223-Ig fusion protein
Concentration: 1.0 - 5.0 mg/ml
Formulation: Sterile filtered & formulated in 0.01 M phosphate buffered saline (PBS) pH 7.4 with no preservatives.
Purity: >98% by SDS-PAGE and HPLC
Endotoxin: ≤ 0.5 EU/mg as determined by the LAL method
Aggregation: Aggregation level ≤ 1%
Use: Products are for research use only. Not for use in diagnostic or therapeutic procedures.
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