Anti-Mouse GM-CSF In Vivo Antibody - Ultra Low Endotoxin (MP1-22E9)

Target: GM-CSF.

Clone: MP1-22E9.

Specificity: Anti-GM-CSF In Vivo Antibody - Ultra Low Endotoxin (MP1-22E9) recognizes an epitope on Mouse GM-CSF.

Purification method: This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.

Background: Granulocyte-macrophage colony-stimulating factor, often abbreviated to GM-CSF is a pleiotropic cytokine that controls the production and function of blood cells. GM-CSF stimulates stem cells to produce granulocytes (neutrophils, eosinophils, and basophils) and monocytes.GM-CSF has a critical role in regulation of surfactant homeostasis and alveolar macrophage innate immune functions in the lung.

Immunogen: Yeast Derived Recombinant Mouse GM-CSF.

Concentration: ≥ 2.0 mg/ml.

Formulation: 0.2 µm filtered and lyophilized from modified Dulbecco's phosphate buffered saline (1X PBS) pH 7.2 - 7.3 containing 5.0% w/v trehalose with no calcium, magnesium or preservatives present.

Purity: >98% by SDS-PAGE and HPLC.

Endotoxin: ≤ 0.75 EU/mg as determined by the LAL method.

Aggregation: Aggregation level ≤ 1%.

Use: Products are for research use only. Not for use in diagnostic or therapeutic procedures.