Species: Human
Product Description: G-CSF (Granulocyte-colony stimulating factor/CSF3) is the major growth factor driving the generation of mature granulocytes from committed bone marrow myeloid progenitors. This biologically active recombinant human G-CSF is an 18.7 kDa globular protein formed by a 174-amino acid polypeptide with two intramolecular disulfide bonds. Human and murine G-CSFs are highly similar and show reciprocal biological cross-reactivity.
Application Note: Recommended antibody pairs for sandwich ELISA:
Capture: GTX641067 or Detection: GTX641068
Form: Lyophilized powder
Buffer (with preservative): Reconstitute with ddH₂O to 0.1 mg/ml. Lyophilized from 50mM PBS (pH7.4), 200mM NaCl, 5% Trehalose, no preservative.
Concentration:
Background: The protein encoded by this gene is a cytokine that controls the production, differentiation, and function of granulocytes. The active protein is found extracellularly. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, May 2010]
Uniprot ID: P09919
Region Sequence: Human full-length G-CSF protein (31-204 a.a. of NP_757373.1, signal peptide removed)
ExpressionSystem: E. Coli
Conjugation: Unconjugated
Full Name: colony stimulating factor 3