English
Human IL1 Receptor 2 protein, His tag (active)
Human IL1 Receptor 2 protein, His tag (active)
Artikelnummer
GTX67059-PRO-10
Verpackungseinheit
10 μg
Hersteller
GeneTex
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Clone Name:
Species: Human
Application Note: Measured by its ability to inhibit proliferation using D10.G4.1 mouse helper T cells. The ED₅₀ for this effect is less or equal to 400 ng/ml with IL-1 beta.
Form: Liquid
Buffer (with preservative): PBS (pH7.4), 10% Glycerol, no preservative.
Concentration: 0.5 mg/ml (Please refer to the vial label for the specific concentration.)
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Background: The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This protein binds interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor, type I(IL1R1/IL1RA), and acts as a decoy receptor that inhibits the activity of its ligands. Interleukin 4 (IL4) is reported to antagonize the activity of interleukin 1 by inducing the expression and release of this cytokine. This gene and three other genes form a cytokine receptor gene cluster on chromosome 2q12. Alternative splicing results in multiple transcript variants and protein isoforms. Alternative splicing produces both membrane-bound and soluble proteins. A soluble protein is also produced by proteolytic cleavage. [provided by RefSeq, May 2012]
Uniprot ID: P27930
Region Sequence: C-terminal His-Tag; Length: 338 a.a. Sequence: FTLQPAAHTG AARSCRFRGR HYKREFRLEG EPVALRCPQV PYWLWASVSP RINLTWHKND SARTVPGEEE TRMWAQDGAL WLLPALQEDS GTYVCTTRNA SYCDKMSIEL RVFENTDAFL PFISYPQILT LSTSGVLVCP DLSEFTRDKT DVKIQWYKDS LLLDKDNEKF LSVRGTTHLLVHDVALEDAG YYRCVLTFAH EGQQYNITRS IELRIKKKKE ETIPVIISPL KTISASLGSR LTIPCKVFLG TGTPLTTMLW WTANDTHIES AYPGGRVTEG PRQEYSENNE NYIEVPLIFD PVTREDLHMD FKCVVHNTLS FQTLRTTVKE LEHHHHHH
ExpressionSystem: Baculovirus
Conjugation: Unconjugated
Full Name: interleukin 1 receptor type 2
Species: Human
Application Note: Measured by its ability to inhibit proliferation using D10.G4.1 mouse helper T cells. The ED₅₀ for this effect is less or equal to 400 ng/ml with IL-1 beta.
Form: Liquid
Buffer (with preservative): PBS (pH7.4), 10% Glycerol, no preservative.
Concentration: 0.5 mg/ml (Please refer to the vial label for the specific concentration.)
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Background: The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This protein binds interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor, type I(IL1R1/IL1RA), and acts as a decoy receptor that inhibits the activity of its ligands. Interleukin 4 (IL4) is reported to antagonize the activity of interleukin 1 by inducing the expression and release of this cytokine. This gene and three other genes form a cytokine receptor gene cluster on chromosome 2q12. Alternative splicing results in multiple transcript variants and protein isoforms. Alternative splicing produces both membrane-bound and soluble proteins. A soluble protein is also produced by proteolytic cleavage. [provided by RefSeq, May 2012]
Uniprot ID: P27930
Region Sequence: C-terminal His-Tag; Length: 338 a.a. Sequence: FTLQPAAHTG AARSCRFRGR HYKREFRLEG EPVALRCPQV PYWLWASVSP RINLTWHKND SARTVPGEEE TRMWAQDGAL WLLPALQEDS GTYVCTTRNA SYCDKMSIEL RVFENTDAFL PFISYPQILT LSTSGVLVCP DLSEFTRDKT DVKIQWYKDS LLLDKDNEKF LSVRGTTHLLVHDVALEDAG YYRCVLTFAH EGQQYNITRS IELRIKKKKE ETIPVIISPL KTISASLGSR LTIPCKVFLG TGTPLTTMLW WTANDTHIES AYPGGRVTEG PRQEYSENNE NYIEVPLIFD PVTREDLHMD FKCVVHNTLS FQTLRTTVKE LEHHHHHH
ExpressionSystem: Baculovirus
Conjugation: Unconjugated
Full Name: interleukin 1 receptor type 2
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Gernot Ensinger, M.Sc.
Laurent Haze
