Rabbit anti Human Programmed cell death protein 1

Rabbit anti Human Programmed cell death protein 1, Polyclonal, Ig

Background: Inhibitory cell surface receptor involved in the regulation of T-cell function during immunity and tolerance. Upon ligand binding, inhibits T-cell effector functions in an antigen-specific manner. Possible cell death inducer, in association with other factors.

Positive Control: Human kidney.

Immunogen: Synthetic peptide derived from the human PD1 protein.

Purification Method: Antigen Immunoaffiinity Purification.

Formulation: Provided as solution in phosphate buffered saline with 0.08% sodium azide.

References: 1. Shinohara, T., et al. ‘Structure and chromosomal localization of the human PD-1 gene (PDCD1)” Genomics, 23, 704-706 (1994)
2. Fife, B.T., Pauken, K.E. ‘The role of the PD-1 pathway in autoimmunity and peripheral tolerance.” Ann. N.Y. Acad. Sci., 1217, 45-59 (2011).

UniProt: Q15116.

Caution: This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals.

• Artikelnummer: EXAX2798P
• Hersteller: Exalpha Biologicals Inc
• Hersteller Artikelnummer: X2798P
• Verpackungseinheit: 100 µg
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Polyclonal
• Methode: Western Blotting, Immunohistochemistry
• Isotyp: Ig
• Wirt: Rabbit