Product Description: 5-Formyl-2'-deoxyuridine is a product formed when the 5-methyl group of thymine in DNA undergoes oxidation due to exposure to gamma radiation or certain chemical agents. Serving as a biomarker of oxidative DNA damage, 5-formyl-2'-deoxyuridine is employed in investigations of DNA damage and repair mechanisms. Additionally, 5-Formyl-2'-deoxyuridine can be used in studies involving chemically crosslinking with peptides derived from the RecA protein[1].
Applications: Metabolism-protein/nucleotide metabolism
Formula: C10H12N2O6
References: [1]Sugiyama T, et al. Chemical cross-linking of peptides derived from RecA with single-stranded oligonucleotides containing 5-formyl-2′-deoxyuridine[J]. Nucleosides, Nucleotides and Nucleic Acids, 2001, 20(4-7): 1079-1083.
CAS Number: 4494-26-2
Molecular Weight: 256.21
Compound Purity: 99.64
Research Area: Others
Solubility: DMSO : 200 mg/mL (ultrasonic)
Target: Endogenous Metabolite
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