AZD 3147, CAS 1101810-02-9

Shelf life (days): 1460.0

Formulation: A solid

Formal Name: N-[4-[4-[1-(cyclopropylsulfonyl)cyclopropyl]-6-[(3S)-3-methyl-4-morpholinyl]-2-pyrimidinyl]phenyl]-N'-(2-hydroxyethyl)-thiourea

Purity: ≥95%

Formula Markup: C24H31N5O4S2

Formula Weight: 517.7

CAS Number: 1101810-02-9

Notes: AZD 3147 is an orally bioavailable dual inhibitor of mammalian target of rapamycin complex 1 (mTORC1) and mTORC2 (IC50s = 40.7 and 5.75 nM, respectively, in MDA-MB-468 cells).{55175} It is selective for mTOR over PI3Kα, PI3Kβ, PI3Kδ, and PI3Kγ (IC50s = 1.51, 912, 5,495, 9,333, and 6,310 nM, respectively, in enzyme assays).

• Artikelnummer: CAY22474-1
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 22474-1
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK