CD137 (4-1BB), Fc fusion (Human) HiP™ Recombinant

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Encompassing Amino Acids: 24-186

Applications: Useful for studying protein binding and screening small molecular inhibitors

Description: Human secreted CD137, Fc fusion protein, also known as Tumor Necrosis Factor Receptor Superfamily member 9, TNFRSF9, and ILA, GenBank Accession No. NM_001561, a.a. 24-186 expressed in a HEK293 cell expression system. MW = 44 kDa (monomer). This protein runs at a higher MW by SDS-PAGE due to glycosylation.

Endotoxin Level: <1 EU/µg

Format: Aqueous buffer solution

Formulation: 40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, and 20% glycerol

Genbank: NM_001561

Storage Stability: At least 6 months at -80°C.

Tags: C-terminal Fc fusion (Human IgG1)

Uniprot: Q07011

Warnings: Avoid freeze/thaw cycles. Protein may be diluted to ≥100 µg/ml in PBS + glycerol and stored at -80°C.

Biosafety Level: Not applicable (BSL-1)

References: 1. Wilcox, R.A., et al., J. Clin. Invest. 2002; 109(5): 651-659.2. Foell, J. et al., J. Clin. Invest. 2003; 111(10): 1505-1518.

• Artikelnummer: BPS71170
• Hersteller: BPS Bioscience
• Hersteller Artikelnummer: 71170
• Green Labware: Nein
• Verpackungseinheit: 100 µg
• Mengeneinheit: STK