GITR (CD357), Fc fusion (Human) HiP™ Recombinant

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Encompassing Amino Acids: 26-161

Applications: Useful for studying protein binding and screening small molecular inhibitors

Description: Human secreted GITR, Fc fusion protein, also known as Glucocorticoid-induced TNFR-Related Protein, Tumor Necrosis Factor Receptor Superfamily member 18, TNFRSF18, Activation-Inducible TNFR Family Receptor, AITR, and CD357, GenBank Accession No. NM_004195, a.a. 26-161 expressed in a HEK293 cell expression system. MW = 41.2 kDa (monomer). This protein runs at a higher MW by SDS-PAGE due to glycosylation.

Endotoxin Level: <1 EU/µg

Format: Aqueous buffer solution

Formulation: 40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, and 20% glycerol

Genbank: NM_004195

Storage Stability: At least 6 months at -80°C.

Tags: C-terminal Fc fusion (Human IgG1)

Uniprot: Q9Y5U5

Warnings: Avoid freeze/thaw cycles. Protein may be diluted to ≥100 µg/ml in PBS + glycerol and stored at -80°C.

Biosafety Level: Not applicable (BSL-1)

References: 1. Shimizu, J., et al., Nat. Immunol. 2002; 3: 135-142.
2. Ko, K., et al., J. Exp. Med. 2005; 202(7): 885-891.

• Artikelnummer: BPS71172
• Hersteller: BPS Bioscience
• Hersteller Artikelnummer: 71172
• Green Labware: Nein
• Verpackungseinheit: 100 µg
• Mengeneinheit: STK