Ferristatin II, CAS 1937-37-7

Shelf life (days): 1460.0

Formulation: A solid

Formal Name: 4-amino-3-[2-[4'-[2-(2,4-diaminophenyl)diazenyl][1,1'-biphenyl]-4-yl]diazenyl]-5-hydroxy-6-(2-phenyldiazenyl)-2,7-naphthalenedisulfonic acid, disodium salt

Formula Markup: C34H25N9O7S2 / 2Na

Formula Weight: 781.7303

CAS Number: 1937-37-7

Notes: Ferristatin II is an inhibitor of iron uptake.{65353} It inhibits iron uptake (IC50 = ~12 µM), as well as induces degradation of transferrin receptor protein 1 (TfR1), an effect that can be reversed by the lipid membrane disruptor nystatin, in HeLa cells. In vivo ferristatin II (0.2, 10, and 40 mg/kg) reduces serum iron levels and transferrin saturation in rats. It also suppresses traumatic brain injury-induced lipid peroxidation, neuronal apoptosis, and the number of cortical iron deposits in rats.{65354}

• Artikelnummer: CAY36621-50
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 36621-50
• Verpackungseinheit: 50 g
• Mengeneinheit: STK
• Methode: Reinstoffe