Shelf life (days): 1825.0
Formulation: A crystalline solid
Formal Name: 5-(3-(1-naphthoyl)-1H-indol-1-yl-2,4,5,6,7-d5)pentanoic acid
Purity: ≥99% deuterated forms (d1-d5)
Formula Markup: C24H16D5NO3
Formula Weight: 376.5
CAS Number: 2748533-42-6
Notes: JWH 018 N-pentanoic acid metabolite-d5 contains five deuterium atoms at the 2, 4, 5, 6, and 7 positions. It is intended for use as an internal standard for the quantification of JWH 018 N-pentanoic acid metabolite (Item No. 9000856) by GC- or LC-mass spectrometry (MS). JWH 018 is a mildly selective agonist of the peripheral cannabinoid (CB2) receptor, derived from the aminoalkylindole WIN 55,212-2. The Ki values for binding central cannabinoid (CB1) and CB2 receptors are 9.0 and 2.94 nM, respectively, for a CB1:CB2 ratio of 3.06.{16797} JWH 018 is one of several synthetic CBs which have been included in smoking mixtures. JWH 018 N-pentanoic acid metabolite is a minor urinary metabolite of JWH 018, characterized by carboxylation of the N-alkyl chain.{18291} In urine samples, this metabolite is almost completely glucuronidated.{18291}
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