Products from BPS Bioscience require a minimum order value above 400€Encompassing Amino Acids: full length
Application: Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
Assay Conditions: Enzyme reaction is conducted usingBPS's PARP6 Assay Kit (Catalog #80556) at room temperature for 1 hour.
Description: Human PARP6 (GenBank Accession No. NM_020214), full length with N-terminal GST-tag, MW = 98 kDa, expressed in a Baculovirus infected Sf9 cell expression system.
Format: Aqueous buffer solution
Formulation: 40 mM Tris-HCl, pH 8.0,120 mM NaCl, 0.04% Tween-20, 16 mMglutathione, 20% glycerol, and 3 mM DTT.
Genbank: NM_020214
Storage Stability: At least 6 months at -80°C.
Tags: N-terminal GST-tag
Uniprot: Q2NL67
Unit Definition: One unit of PARP incorporates 100 pmoles of poly(ADP) in 1 minute from NAD into the acid-insoluble form.
Warnings: Avoid freeze/thaw cycles.
Biosafety Level: Not applicable (BSL-1)
References: 1. Ame,J.C., Spenlehauer,C. and de Murcia,G. Bioessays 26 (8), 882-893 (2004).
2. Hassa PO and Hottiger MO. Front Biosci. 1;13:3046-82 (2008). Application Reference(s):
Fragment-based ligand design of novel potent inhibitors of tankyrases (2013)
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