CD18 antibody (MEM-148) (Low Endotoxin)

Clone Name: MEM-148

Calculated MW: 85

Specificity/Sensitivity: This antibody recognizes an epitope on CD18 which is essentially inaccessible in intact integrin molecules on resting leukocytes, but is exposed on high-affinity state of LFA-1 or on unassociated CD18.,We do not recommend use of this product for Pig.

Form: Liquid

Buffer (with preservative): 0.2μm filter-sterilized PBS, no preservative.

Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration.)

Background: This gene encodes an integrin beta chain, which combines with multiple different alpha chains to form different integrin heterodimers. Integrins are integral cell-surface proteins that participate in cell adhesion as well as cell-surface mediated signalling. The encoded protein plays an important role in immune response and defects in this gene cause leukocyte adhesion deficiency. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014]

Uniprot ID: P05107

Antigen Species: Human

Immunogen: Peripheral blood mononuclear cells

Purification: Protein A purified

Conjugation: Unconjugated

Full Name: integrin subunit beta 2