1,3-PBIT (dihydrobromide), CAS 200716-66-1

Product Description: 1,3-PBIT is a potent inhibitor of iNOS with a Ki of 47 nM compared to Ki values for eNOS and nNOS are 9 and 0.25 μM, respectively, for the purified human enzymes. Its inhibition in whole cells is greatly diminished, presumably to poor membrane permeability.

Applications: COVID-19-immunoregulation

Formula: C12H20Br2N4S2

References: [1]Garvey, et al. Potent and selective inhibition of human nitric oxide synthases. Inhibition by non-amino acid isothioureas. J. Biol. Chem. 269(43), 26669-26676 (1994).

CAS Number: 200716-66-1

Molecular Weight: 444.25

Research Area: Inflammation/Immunology

Target: NO Synthase

• SKU: MEXHY-120865-10
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-120865-10
• Package Unit: 10 mg
• Quantity Unit: STK