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ADC Related

ADC Related

The ADC, antibody-drug conjugate, a humanised or human monoclonal antibody with conjugated highly potent cytotoxic small molecules (payloads), is a novel therapeutic format with great potential for a paradigm shift in cancer chemotherapy. The three components of the ADC form a powerful oncolytic agent capable of delivering normally untolerated cytotoxins directly to cancer cells, which then internalise and release the cytotoxic drugs. Currently, two ADCs, Adcetris and Kadcyla, have received marketing authorisation and more than 40 others are in clinical development.

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  1. Mal((3S,3aR,6S,6aR)-Hexahydrofuro(3,2-b)furan-3,6-diamine-PEG12)-β-Glu-PAB
    Mal((3S,3aR,6S,6aR)-Hexahydrofuro(3,2-b)furan-3,6-diamine-PEG12)-β-Glu-PAB
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    Sku MEXHY-173635-0
    Manufact. SkuHY-173635-0
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  2. Mal((3S,3aR,6S,6aR)-Hexahydrofuro(3,2-b)furan-3,6-diamine-PEG12)-β-Glu-PAB-Exatecan, CAS 3059991-66-8
    Mal((3S,3aR,6S,6aR)-Hexahydrofuro(3,2-b)furan-3,6-diamine-PEG12)-β-Glu-PAB-Exatecan, CAS 3059991-66-8
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    Sku MEXHY-173634-0
    Manufact. SkuHY-173634-0
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  3. BrAc-Val-Ala
    BrAc-Val-Ala
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    Sku MEXHY-173633-0
    Manufact. SkuHY-173633-0
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  4. P5(PEG12)-VC-PAB-Exatecan, CAS 2928571-52-0
    P5(PEG12)-VC-PAB-Exatecan, CAS 2928571-52-0
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    Sku MEXHY-173625-0
    Manufact. SkuHY-173625-0
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  5. Cys-MC-GGFG-Dxd, CAS 3025787-83-8
    Cys-MC-GGFG-Dxd, CAS 3025787-83-8
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    Sku MEXHY-176415-0
    Manufact. SkuHY-176415-0
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  6. Mal-amide-PEG8-Val-Cit-PAB-PNP, CAS 1964490-09-2
    Mal-amide-PEG8-Val-Cit-PAB-PNP, CAS 1964490-09-2
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    Sku MEXHY-172291-0
    Manufact. SkuHY-172291-0
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  7. Benzyl N1-(PEG1-NHS)-N6-(t-Boc)-L-lysinate, CAS 2639400-46-5
    Benzyl N1-(PEG1-NHS)-N6-(t-Boc)-L-lysinate, CAS 2639400-46-5
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    Sku MEXHY-172290-0
    Manufact. SkuHY-172290-0
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  8. DBCO-PEG2-Val-Cit-PAB-MMAE, CAS 2845934-59-8
    DBCO-PEG2-Val-Cit-PAB-MMAE, CAS 2845934-59-8
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    Sku MEXHY-172287-0
    Manufact. SkuHY-172287-0
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  9. Mc-d-Val-d-Cit-PAB-PNP, CAS 1350456-68-6
    Mc-d-Val-d-Cit-PAB-PNP, CAS 1350456-68-6
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    Sku MEXHY-173161-0
    Manufact. SkuHY-173161-0
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  10. Val-Ala-PAB-SN38, CAS 3025787-76-9
    Val-Ala-PAB-SN38, CAS 3025787-76-9
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    Sku MEXHY-173243-0
    Manufact. SkuHY-173243-0
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