Shelf life (days): 730.0
Assay Range: 2.3-5,000 pg/ml
Sensitivity: 80% B/B0: 15 pg/ml
Cross Reactivity: 13,14-dihydro-15-keto Prostaglandin F2α 100%; 13,14-dihydro-15-keto Prostaglandin E2 2.7%; 15-keto Prostaglandin F2α 1.8%; Prostaglandin D2 <0.01%; Prostaglandin E2 <0.01%; Prostaglandin F1α <0.01%; 2,3-dinor-6-keto Prostaglandin F1α <0.01%; 6-keto Prostaglandin F1α <0.01%; Prostaglandin F2α <0.01%; 8-iso Prostaglandin F2α <0.01%; 8-iso-13,14-dihydro-15-keto Prostaglandin F2α <0.01%; 8-iso-15-keto Prostaglandin F2α <0.01%; Prostaglandin F2β <0.01%; 8-iso Prostaglandin F3α <0.01%; Thromboxane B2 <0.01%
Formula Weight: 0.0
Notes: PGF2α is rapidly metabolized to 13,14-dihydro-15-keto PGF2α in vivo, by the enzymes 15-hydroxy PG dehydrogenase and D13-reductase. Measurement of 13,14-dihydro-15-keto PGF2α in plasma can be used as a marker of the in vivo production of PGF2α. The Cayman’s 13,14-dihydro-15-keto PGF2α ELISA is a competitive assay that provides measurements of 13,14-dihydro-15-keto PGF2α within the range of 2.3-5,000 pg/ml. The assay has been validated for the measurement of 13,14-dihydro-15-keto PGF2α in plasma, a common matrix for measurement of this PGF2α metabolite.
English
Deutsch
