Shelf life (days): 1460
Info: A GC-A antagonist (Ki = 0.66 nM); inhibits cGMP production induced by ANP in NB-OK-1 cells (pA2 = 9.48); induces dilation and increases glomerular blood flow in rat hydronephrotic renal vascular segments but inhibits ANP-induced dilation in the same preparations at 1 µM; prevents BNP-induced increases in spontaneous action potential frequency in isolated mouse sinoatrial node myocytes at 0.5 µM
Formulation: A solid
Formal Name: L-arginyl-L-cysteinyl-3-cyclohexyl-L-alanylglycylglycyl-L-arginyl-L-isoleucyl-L-α-aspartyl-L-arginyl-L-isoleucyl-(3R)-1,2,3,4-tetrahydro-3-isoquinolinecarbonyl-L-arginyl-L-cysteinamide, cyclic (2→13)-disulfide, trifluoroacetate salt
Amino Acids: Cyclo(RCX1GGRIDRIX2RC)-NH2 (X1 = Cyclohexylalanine
Purity: ≥98%
Formula Markup: C69H116N26O15S2 • XCF3COOH
Formula Weight: 1613.974
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