Clone Name: 2J39
Application Note: ICC/IF: 1:100 - 1:1000. FCM: 1:100 - 1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Form: Liquid
Buffer (with preservative): PBS, no preservative.
Concentration: 200 μg/ml (Please refer to the vial label for the specific concentration.)
Background: The membrane-associated protein encoded by this gene is included in the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. Alternatively referred to as a breast cancer resistance protein, this protein functions as a xenobiotic transporter which may play a major role in multi-drug resistance. It likely serves as a cellular defense mechanism in response to mitoxantrone and anthracycline exposure. Significant expression of this protein has been observed in the placenta, which may suggest a potential role for this molecule in placenta tissue. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]
Uniprot ID: Q9UNQ0
Antigen Species: Human
Immunogen: Human recombinant rHABCG2 protein
Purification: Protein G purified
Conjugation: Unconjugated
Full Name: ATP binding cassette subfamily G member 2 (Junior blood group)
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