Conjugation: FITC: Fluorescein Isothiocyanate
Description of Target: ADAM2 is a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. ADAM2 is a subunit of an integral sperm membrane glycoprotein called fertilin, which plays an important role in sperm-egg interactions.This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This member is a subunit of an integral sperm membrane glycoprotein called fertilin, which plays an important role in sperm-egg interactions.
Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ADAM2
Key Reference: Eto,K., (2002) J. Biol. Chem. 277 (20), 17804-17810
Molecular Weight: 81kDa
Peptide Sequence: Synthetic peptide located within the following region:
PHDVAFLLVYREKSNYVGATFQGKMCDANYAGGVVLHPRTISLESLAVILProduct Format: Liquid. Purified antibody supplied in 1x PBS buffer.
Protein Name: Disintegrin and metalloproteinase domain-containing protein 2
Protein Size: 735
Purification: Affinity Purified
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