Adatanserin (hydrochloride), CAS 144966-96-1

Product Description: Adatanserin hydrochloride is a high affinity, selective and partial agonist for the 5-HT1A receptor with a Ki of 1 nM. Adatanserin hydrochloride is a moderate affinity 5-HT2 receptor antagonist with a Ki of 73 nM. Adatanserin hydrochloride shows significant anxiolytic and antidepressant activity in an animal conflict model[1][2].

Formula: C21H32ClN5O

References: [1]M A Abou-Gharbia, et al. Synthesis and SAR of adatanserin: novel adamantyl aryl- and heteroarylpiperazines with dual serotonin 5-HT(1A) and 5-HT(2) activity as potential anxiolytic and antidepressant agents. /[2]A Singh, et al. Antidepressant-like activity of compounds with varying efficacy at 5-HT1A receptors. Neuropharmacology. 1993 Apr;32(4):331-40.

CAS Number: 144966-96-1

Molecular Weight: 405.96

Research Area: Neurological Disease

Target: 5-HT Receptor

• SKU: MEXHY-121053A-10
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-121053A-10
• Package Unit: 10 mg
• Quantity Unit: STK