Product Description: AEEA-AEEA is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). AEEA-AEEA is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.
Applications: Cancer-programmed cell death
Formula: C12H24N2O7
References: [1]Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017;16(5):315-337./[2]Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985.
CAS Number: 1143516-05-5
Molecular Weight: 308.33
Compound Purity: 99.12
Research Area: Cancer
Solubility: DMSO : < 1 mg/mL (ultrasonic;warming;heat to 60°C)