AMG-151, CAS 1138669-65-4

Product Description: AMG-151 (ARRY-403) is a glucokinase agonist with fasting plasma glucose (FPG) lowering activity. AMG-151 showed a significant linear dose-response trend compared with placebo in a randomized, placebo-controlled Phase IIa study. The use of AMG-151 was associated with a higher incidence of hypoglycemia and hypertriglyceridemia. AMG-151 may serve as a potential compound for the inhibition of type 1 diabetes[1].

Applications: Metabolism-protein/nucleotide metabolism

Formula: C20H18N6O3S2

References: [1]AMG 151 (ARRY-403), a novel glucokinase activator, decreases fasting and postprandial glycaemia in patients with type 2 diabetes

CAS Number: 1138669-65-4

Molecular Weight: 454.53

Research Area: Metabolic Disease

Target: Endogenous Metabolite

• SKU: MEXHY-125316-1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-125316-1
• Package Unit: 1 mg
• Quantity Unit: STK