Shelf life (days): 1460
Info: A 5-HT2A and dopamine D2 receptor antagonist; selective for the 5-HT2A receptor over 5-HT2B and 5-HT1C receptors (Kis = 22.39, 977.24, and 1,548.82 nM, respectively) but does bind to the 5-HT1A receptor (Ki = 50 nM); selectively binds to the dopamine D2 receptor over the dopamine D1 receptor (Kis = 3 and 2,530 nM, respectively); completely inhibits amphetamine-induced increases in locomotor activity and rearing behavior in rats for at least three hours at 0.05 mg/kg; reduces amphetamine-induced increases in locomotor activity and rearing behavior in mice when used at doses of 0.15 and 0.2 mg/kg but the effects only last for 30 minutes
Formulation: A solid
Formal Name: 8-[3-(4-fluorophenoxy)propyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one
Purity: ≥98%
Formula Markup: C22H26FN3O2
Formula Weight: 383.467403
CAS Number: 510-74-7
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