AMPte-Glu-γ-Glu, CAS 41600-13-9

Product Description: AMPte-Glu-γ-Glu is a substrate for folylpoly-γ-glutamate synthetase (FPGS). AMPte-Glu-γ-Glu exhibits cytotoxicity against chinese hamster ovaries cells, with IC50s of 20, 350 and 3 nM, for Pro3, R2, and 43-10, respectively[1].

Applications: Cancer-programmed cell death

Formula: C25H29N9O8

References: [1]Feng Y, et al., Prodrug forms of N-[(4-deoxy-4-amino-10-methyl)pteroyl]glutamate-gamma-[psiP(O)(OH)]-glutarate, a potent inhibitor of folylpoly-gamma-glutamate synthetase: synthesis and hydrolytic stability. J Med Chem. 2006 Jan 26;49(2):770-88.

CAS Number: 41600-13-9

Molecular Weight: 583.55

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: Antifolate

• SKU: MEXHY-122259-5
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-122259-5
• Package Unit: 5 mg
• Quantity Unit: STK