Description: Human EGF (Epidermal Growth Factor) is a recombinant protein composed of 53 amino acids with 3 intramolecular disulfide-bonds. It is mapped to human chromosome 4q25-27 and is expressed in a variety of organs, including the kidney, salivary gland, cerebrum, and prostate. Human EGF is a powerful URG (urogastrone) hormone, which has been proven to be effective in stimulating the growth of skin cells, among other functions. This human EGF is a 6.2kDa globular protein, making it easy to use for a variety of scientific studies and applications. EGF has been used in the culture medium for the maintenance of MCF10A cells (human mammary epithelial cells).
Published Species: Human, Monkey, Mouse, Pig, Rat
Expression System: E. coli
Molecular Weight: 6.2 kDa
Class: Recombinant
Endotoxin Concentration: <0.1 EU/µg
Activity: The ED50 was determined by a cell proliferation assay using balb/c 3T3 cells is ≤ 0.1 ng/ml, corresponding to a specific activity of ≥ 1 x 10^7 units/mg.
Form: Lyophilized
Contains: no preservative
Storage Conditions: -20°C
Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses
Caution: For Research Use Only. Not for use in diagnostic procedures.
Gene Symbol: EGF
Protein ID: P01133
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