Anti-BAX (3C10)

Anti-BAX [3C10], Recombinant, IgG kappa, Rabbit

CloneID: 3C10

Buffer Composition: PBS only.

Uniprot Accession No.: Q07812

Specificity Statement: The antibody is specific for Bax. It recognizes a peptide encompassing residues 31–45 at the start of Bax a1–a2 loop (AAs RAGRM).

Application Notes (Clone): The specificity of the antibody for Bax was determined by ELISA analysis. The antibody was able to bind to mitochondrial Bax and WT Bax by western blot analysis. The antibody immunoprecipitated Bax (Iyer et al., 2016; PMID: 27217060). The crystal structure of the Fab fragment in complex with BAX was determined. The antibody activates mitochondrial Bax, but blocks translocation of cytosolic Bax (Robin et al., 2018; PMID: 30122452).

• SKU: ABAAb03962-23.0-BT
• Manufacturer: Absolute Antibody
• Manufacturer SKU: Ab03962-23.0-BT
• Package Unit: 1 mg
• Quantity Unit: STK
• Reactivity: Human
• Clonality: Recombinant
• Application: Immunoprecipitation, Western Blotting, ELISA, Crystallography
• Isotype: IgG kappa
• Host: Rabbit