CloneID: 4A5
Heavy Chain modification: Fc Silent™
Antigen Long Description: The original antibody was generated by immunizing mice with human CD147.
Buffer Composition: PBS only.
Chimeric Use Statement: This is a reformatted human IgG1 Fc Silent™ antibody, based on the original human Fab format, created for improved compatibility with existing reagents, assays and techniques.
Uniprot Accession No.: P35613
Specificity Statement: The antibody binds to human CD147.
Application Notes (Clone): The specificity of the original format of the antibody was confirmed by ELISA analysis. The affinity of the Fab fragment of the antibody for the CD147 His-tagged N-terminal domain was 120 nM, as measured by Surface Plasmon Resonance. Further, the antibody was used for affinity maturation studies (US20100261620).