CloneID: ABL-1
Antigen Long Description: The original antibody was generated by immunizing mice with human BAFF protein.
Buffer Composition: PBS with 0.02% Proclin 300.
Available Custom Conjugation Options: AP, HRP, Fluorescein, APC, PE, Biotin Type A, Biotin Type B, Streptavidin, FluoroProbes 647H, Atto488, APC/Cy7, PE/Cy7
Uniprot Accession No.: Q9Y275
Specificity Statement: This antibody binds human BAFF protein. B-cell-activating factor (BAFF/CD257) is a cytokine belonging to the tumour-necrosis factor (TNF) family. This cytokine binds to TNFRSF13B/TACI, TNFRSF17/BCMA, and TNFRSF13C/BAFF-R. BAFF is a survival factor for B cells that controls B-cell maturation. It is also involved in the stimulation of B- and T-cell function and the regulation of humoral immunity.
Application Notes (Clone): This antibody binds recombinant human BAFF (amino acids A134-L285) with a binding affinity of 0.9 X 10^(-8) M. This antibody does not cross react with APRIL protein. This antibody was also capable of detecting native and recombinant forms of human BAFF protein in a western blot assay (PMID: 16023370).
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