Anti-CD28 (PV1)

Anti-CD28 [PV1], Recombinant, IgG1 kappa, Human

CloneID: PV1

Antigen Long Description: The antibody was generated using C57BL/6N mouse T cell lymphoma EL4 cell line as antigen.

Buffer Composition: PBS only.

Uniprot Accession No.: P31041

Specificity Statement: The antibody binds specifically to murine CD28.

Application Notes (Clone): CD28-positive murine T cell line EL4 cells were stained with the antibody and analyzed by flow cytometry (US20040116675A1). Protein lysates from J558 were immunoprecipitated with the antibody (Rozanski et al., 2015; PMID: 25833397). Anti-CD28-PV1-IgG3 is the hamster-mouse chimeric version of the antibody. The antibody enabled long-term survival of heart allografts in rats by reducing the activation of alloantigen-mediated key signaling events in T cells (Jang et al. 2008; PMID: 18408588).

• SKU: ABAAb03857-10.0-BT
• Manufacturer: Absolute Antibody
• Manufacturer SKU: Ab03857-10.0-BT
• Package Unit: 1 mg
• Quantity Unit: STK
• Reactivity: Mouse (Murine)
• Clonality: Recombinant
• Application: Immunoprecipitation, Flow Cytometry
• Isotype: IgG1 kappa
• Host: Human