Anti-CD8 (51.1)

Anti-CD8 [51.1], Recombinant, IgG1 kappa, Human

CloneID: 51.1

Heavy Chain modification: Fc Silent™

Antigen Long Description: The original antibody was generated by immunizing mice with CD1d.

Buffer Composition: PBS only.

Chimeric Use Statement: This is a reformatted human IgG1 Fc Silent™ antibody, based on the original human IgG2b format, created for improved compatibility with existing reagents, assays and techniques.

Uniprot Accession No.: P01732

Specificity Statement: The antibody is specific for CD8.

Application Notes (Clone): The antibody could block HLA-A2.1-mediated binding to CD8α(+) expressed on CHO cells (Norment et al, 1988; PMID: 3263576). The antibody could also block TLA-mediated binding (Teitell et al., 1991; PMID: 1834760). The antibody was used to localize CD8α to the cell periphery on monocytes using confocal microscopy of permeabilized PBMC. The antibody could detect CD8α by flow cytometry on CD14^hi monocytes from human peripheral blood (Gibbings et al. 2007; PMID: 17678538).

• SKU: ABAAb04357-10.3-BT
• Manufacturer: Absolute Antibody
• Manufacturer SKU: Ab04357-10.3-BT
• Package Unit: 1 mg
• Quantity Unit: STK
• Reactivity: Human
• Clonality: Recombinant
• Application: Flow Cytometry, Blocking
• Isotype: IgG1 kappa
• Host: Human