CloneID: LA5
Antigen Long Description: The original antibody was raised by immunizing a mouse with VACV.
Buffer Composition: PBS with 0.02% Proclin 300.
Available Custom Conjugation Options: AP, HRP, Fluorescein, APC, PE, Biotin Type A, Biotin Type B, Streptavidin, FluoroProbes 647H, Atto488, APC/Cy7, PE/Cy7
Uniprot Accession No.: P04195
Specificity Statement: This antibody is specific for protein D8 of the vaccinia virus. It binds above the CS-E binding crevice
Application Notes (Clone): The original version of this antibody was used for ELISA on recombinant D8 protein. The binding strength of this antibody was also determined using surface plasmon resonance on VAVC D8 (Matho et al., 2012; PMID:22623786). The original antibody was used for neutralization of a intracellular mature virion. It showed that is was only able to neutralize the intracellular mature virion in the present of complement (Matho et al., 2018; PMID:29123031).