CloneID: 5A10
Heavy Chain modification: Fc Silent™
Antigen Long Description: The original antibody was generated by immunizing BALB/c mice with citreoviridin cross-linked with carrier proteins like BSA and KLH.
Buffer Composition: PBS only.
Chimeric Use Statement: This is a reformatted human IgG1 Fc Silent™ antibody, based on the original human IgG1 format, created for improved compatibility with existing reagents, assays and techniques.
Specificity Statement: This antibody binds citreoviridin, which is one of the mycotoxins that contaminates a wide range of agricultural products, including rice, cereal grains and farm crop products. It is produced by Aspergillus terreus, Eupenicillium ochrosalmoneum and Penicillium citreonigrum. It causes cytotoxicity as an uncompetitive inhibitor of ATP hydrolysis. Consuming food which is contaminated with citreoviridin can cause the disease cardiac beri beri.
Application Notes (Clone): The binding reactivity of this antibody for citreoviridin was determined using ELISA. This antibody can be used for detection of citreoviridin in contaminated food samples. Indirect competitive ELISA (ic-ELISA) indicated that the linear range to detect CIT for this antibody was 25-562 ng/mL with IC50 at 120 ng/mL. The limit of detection was 14.7 ng/mL, and the recovery average was (90.612 ± 3.889)% (PMID: 27622814)
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